Friday, 12 August 2016

Sugar addiction: Discovery of a brain sugar switch

Researchers have discovered that our brain actively takes sugar from the blood. Prior to this, researchers around the world had assumed that this was a purely passive process. An international team reports that transportation of sugar into the brain is regulated by so-called glial cells that react to hormones such as insulin or leptin; previously it was thought that this was only possible for neurons. ...

García-Cáceres, C., Quarta, C., Varela, L., Gao, Y., Gruber, T., Legutko, B., Jastroch, M., Johansson, P., Ninkovic, J., Yi, C.... (2016) Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability. Cell, 166(4), 867-880. DOI: 10.1016/j.cell.2016.07.028  




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